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Ketamine mouthwash for mucositis pain
Journal of Palliative Medicine, 09/01/09
Ryan AJ et al. – Ketamine swish and expectorate may be a viable treatment option in refractory mucositis pain.
Methods- A retrospective chart audit was preformed on eight patients who received ketamine mouthwash (20mg/5mL) for refractory mucositis pain.
- All eight patients had mucositis pain refractory to a mucositis mixture (lidocaine, magnesium/aluminum hydroxide, and diphenhydramine) and opioids.
- An improvement in mucositis pain was seen in over half (5/8) of the patients.
- Four of eight patients had adverse effects that could have been associated with the ketamine mouthwash; all side effects were transient and subsided when the ketamine mouthwash was stopped.
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