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The Death Receptor CD95 Activates Adult Neural Stem Cells for Working Memory Formation and Brain Repair
Cell Stem Cell, 08/31/09
Corsini NS et al. – Lack of hippocampal CD95 resulted in a reduction in neurogenesis and working memory deficits. Following global ischemia, CD95–mediated brain repair rescued behavioral impairment. Thus, the authors identify the CD95/CD95L system as an instructive signal for ongoing and injury–induced neurogenesis.
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