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See Latest ArticlesCapecitabine in combination with oxaliplatin or irinotecan in elderly patients with advanced colorectal cancer: results of a randomized phase II study
Annals of Oncology, 09/01/09
Rosati G et al. – CAPOX (capecitabine and oxaliplatin) and CAPIRI (capecitabine and irinotecan)had similar efficacy in elderly patients, although CAPOX was better tolerated.
Methods- 94 patients ≥ 70 years of age with advanced/metastatic CRC randomly assigned to tx with CAPOX and CAPIRI
- 2 CR and 16 PR with CAPOX tx
- 2 CR and 15 PR with CAPIRI tx
- Median TTP 8 and 7 mos with CAPOX and CAPIRI tx, respectively
- Median survival 19.3 and 14.0 mos with CAPOX and CAPIRI tx, respectively
- Global health status increased 45% and 21% with CAPOX and CAPIRI tx, respectively
- Grade 3/4 diarrhea (15% vs. 32%) and neutropenia (6% vs. 23%) with CAPOX and CAPIRI tx, respectively
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Today in Colorectal Cancer/Polyps...keeping you current
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Clinical Benefit of Allogeneic Melanoma Cell Lysate–Pulsed Autologous Dendritic Cell Vaccine in MAGE-Positive Colorectal Cancer Patients
Clinical Cancer Research, 12/11/09
Barriers to Integrating Gene Profiling for Stage II Colon Cancer
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Metastasis-Associated Gene Expression Changes Predict Poor Outcomes in Patients with Dukes Stage B and C Colorectal Cancer
Clinical Cancer Research, 12/11/09
Today in Pharmacology/Therapy...keeping you current
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Clinical Benefit of Allogeneic Melanoma Cell Lysate–Pulsed Autologous Dendritic Cell Vaccine in MAGE-Positive Colorectal Cancer Patients
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Radiation Therapy for Rectal Cancer: Current Status and Future Directions
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Current Progress in Targeted Therapy for Colorectal Cancer
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