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Loss of the Rho GTPase activating protein p190-B enhances hematopoietic stem cell engraftment potential
Blood, 08/28/09
Xu H et al. – The study defines p190–B as a critical transducer element of HSC self renewal activity and long term engraftment, thus suggesting that p190–B is a target for HSC–based therapies requiring maintenance of engraftment phenotype.
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