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Activation of PI3K/mTOR pathway occurs in most adult low-grade gliomas and predicts patient survival
Journal of Neuro-Oncology, 08/27/09
McBride SM et al. – Survival of LGG patients correlates with phosphorylation of S6 protein. This relationship supports the use of selective mTOR inhibitors in the treatment of low grade glioma.
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Today in Basic Science/Genetics...keeping you current
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Integrated Molecular and Clinical Analysis of AKT Activation in Metastatic Melanoma
Clinical Cancer Research, 12/11/09
Analysis of VHL Gene Alterations and their Relationship to Clinical Parameters in Sporadic Conventional Renal Cell Carcinoma
Clinical Cancer Research, 12/11/09
Platelets release novel thiol isomerase enzymes which are recruited to the cell surface following activation
British Journal of Haematology, 12/11/09
Today in Neurologic Oncology...keeping you current
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Intrinsic Gene Expression Profiles of Gliomas Are a Better Predictor of Survival than Histology
Cancer Research, 12/11/09
Glioblastoma Proto-oncogene SEC61gamma Is Required for Tumor Cell Survival and Response to Endoplasmic Reticulum Stress
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Time Trends in Brain Tumor Incidence Rates in Denmark, Finland, Norway, and Sweden, 1974–2003
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