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See Latest ArticlesGhrelin and leptin levels in cachectic patients with cancer of the digestive organs
International Journal of Clinical Oncology, 09/01/09
Takahashi M et al. – Neither weight loss nor the grade of symptoms were directly associated with the increase in ghrelin levels. Additionally, the changes in plasma cytokines (TNF-? and IL-6) and leptin in cachectic cancer patients suggest that these molecules may be useful markers for the evaluation of cancer cachexia.
Methods- Prospective study
- 16 cachetic patients with cancer of the GI tract and 10 healthy volunteers
- Cytokines, ghrelin, and leptin levels were determined
- TNF-alpha, IL-6, IL-1Ra, and ghrelin levels were higher in cachetic patients than healthy volunteers, while leptin levels were lower
Today in Basic Science/Genetics...keeping you current
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Target genes suitable for silencing approaches and protein product interference in ovarian epithelial cancer
Cancer Treatment Reviews, 12/04/09
Dysregulation of Platelet-Derived Growth Factor beta-Receptor Expression by deltaNp73 in Neuroblastoma
Molecular Cancer Research, 12/04/09
Tissue transglutaminase 2 as a biomarker of cervical intraepithelial neoplasia (CIN) and its relationship to p16INK4A and nuclear factor kappaB expression
Virchows Archiv, 12/04/09
Today in GI Oncology...keeping you current
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ML17032 trial: capecitabine/cisplatin versus 5-fluorouracil/cisplatin as first-line therapy in advanced gastric cancer
Expert Review of Anticancer Therapy, 12/04/09
Clinical implications of esophagorespiratory fistulae in patients with esophageal squamous cell carcinoma (SCCA)
Medical Oncology, 12/04/09
Clinicopathological characteristics of primary gastric T-cell lymphoma
Histopathology, 12/04/09
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