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Clinical outcome of concomitant chemoradiotherapy followed by adjuvant temozolomide therapy for glioblastaomas: Single-center experience
Clinical Neurology and Neurosurgery, 09/02/09
Jeon HJ et al. – The median and 2-year survival outcomes in this study are comparable to the previous reports.
Methods- 79 patients with pathologically-confirmed glioblastomas were treated with radiotherapy combined with temozolomide, followed by adjuvant temozolomide
- Median OS was 18.3 mos and the TTP was 6.7 mos
- 1-y and 2-y survival rates were 70.1% and 37.1%, respectively
- The patients with a post-operative KPS > 80 showed more prolonged survival than those who had a KPS < 80 (23.1 mos vs. 13.4 mos)
- Hematologic toxicity occurred in 8.8% of patients
Today in Neurologic Oncology...keeping you current
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Glioblastoma Proto-oncogene SEC61gamma Is Required for Tumor Cell Survival and Response to Endoplasmic Reticulum Stress
Cancer Research, 12/10/09
Intrinsic Gene Expression Profiles of Gliomas Are a Better Predictor of Survival than Histology
Cancer Research, 12/10/09
Time Trends in Brain Tumor Incidence Rates in Denmark, Finland, Norway, and Sweden, 1974–2003
Journal of the National Cancer Institute, 12/10/09
Today in Pharmacology/Therapy...keeping you current
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18FDG-PET-CT in the follow-up of non-small cell lung cancer patients after radical radiotherapy with or without chemotherapy: An economic evaluation
European Journal of Cancer, 12/10/09
MicroRNAs: Predictors and modifiers of chemo- and radiotherapy in different tumour types
European Journal of Cancer, 12/10/09
Phase I trial of 17-dimethylaminoethylamino-17-demethoxygeldanamycin (17-DMAG), a heat shock protein inhibitor, administered twice weekly in patients with advanced malignancies
European Journal of Cancer, 12/10/09
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