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Differential Roles of Insulin-like Growth Factor Receptor– and Insulin Receptor–mediated Signaling in the Phenotypes of
Hepatocellular Carcinoma Cells
Neoplasia, 08/27/09
Chen YW et al. – The authors identify matrix metalloproteinase 2 as a mediator of the invasive phenotype downstream of IGF1R–induced signaling. Thus, studies demonstrate the importance of IGF2–induced signaling in the dissemination of HCC cells.
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