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See Latest ArticlesA phase II study of weekly docetaxel-cisplatin as first-line treatment for advanced non-small cell lung cancer
Journal of Thoracic Oncology, 09/04/09
Binder D et al. – Weekly docetaxel-cisplatin demonstrated comparable efficacy with three-weekly schedules.
Methods- Patients with inoperable stage International Union Against Cancer IIIB (malignant effusion) or IV non-small cell lung cancer received docetaxel (35 mg/m2, 30 minutes infusion) and cisplatin (25 mg/m2, 30 minutes infusion) on days 1, 8, and 15, every 4 weeks for 4 to 6 cycles
- Ondansetron (8 mg) and dexamethasone (8 mg) were given intravenously before chemotherapy
- Twelve of 44 patients achieved an objective response (11 partial, 1 complete, intent-to-treat response rate 27%).
- Median TTP was 4.4 months
- Median survival 9.6 months
- Patients received a median of three full cycles
- Four patients (9%) required dose reductions
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Docetaxel versus docetaxel alternating with gemcitabine as treatments of advanced breast cancer: final analysis of a randomised trial
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Randomized phase III trial comparing docetaxel plus epirubicin versus docetaxel plus capecitabine as first-line treatment in women with advanced breast cancer
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Today in Lung/Thoracic Oncology...keeping you current
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Today in Pharmacology/Therapy...keeping you current
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Comparative proteomic profiling identified sorcin being associated with gemcitabine resistance in non-small cell lung cancer
Medical Oncology, 12/17/09
Anti-tumor activity and mechanisms of a novel vascular disrupting agent, (Z)-3,4?,5-trimethoxylstilbene-3?-O-phosphate disodium (M410)
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A prospective phase II study of cetuximab in combination with XELOX (capecitabine and oxaliplatin) in patients with metastatic and/or recurrent advanced gastric cancer
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