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See Latest ArticlesDrug-metabolising enzymes are down-regulated by hypoxia in differentiated human hepatoma HepaRG cells: HIF-1alpha involvement in CYP3A4 repression
European Journal of Cancer, 08/25/09
Legendre C et al. – Hypoxia down–regulates hepatic DMEs, a phenomenon that might compromise chemotherapy effectiveness in HCC treatment. Thus, HepaRG cells might represent a new in vitro model to test anticancer agents in hypoxic versus normoxic conditions.
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Today in Basic Science/Genetics...keeping you current
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A gene expression signature that predicts the therapeutic response of the basal-like breast cancer to neoadjuvant chemotherapy
Breast Cancer Research and Treatment, 12/09/09
Expression of Hiwi in human esophageal squamous cell carcinoma is significantly associated with poorer prognosis
BMC Cancer, 12/09/09
Tumour markers predictive of successful treatment of breast cancer with primary endocrine therapy in patients over 70 years old: A prospective study
Critical Reviews in Oncology/Hematology, 12/09/09
Today in Hepatobiliary/Pancreas...keeping you current
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Erlotinib 150 mg daily plus chemotherapy in advanced pancreatic cancer: an interim safety analysis of a multicenter, randomized, cross-over phase III trial of the Arbeitsgemeinschaft Internistische Onkologie
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