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See Latest ArticlesA phase II trial of intraperitoneal interleukin-2 in patients with platinum-resistant or platinum-refractory ovarian cancer
Cancer Immunology, Immunotherapy, 08/27/09
Vlad AM et al. – IP IL-2 is associated with immune correlates of survival in patients with persistent or progressive ovarian cancer
Methods- Phase II clinical trial
- IP rIL-2 infusions qw
- 31 patients with persistent or progressive ovarian cancer
- Well-tolerated
- 4 CR and 2 PR
- ORR 25%
- Median survival 2.1 y
- Peripheral blood eosinophils were markedly increased at the end of tx and associated with increased circulating eotaxin
- Significant associations between changes in CD3 counts and survival
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Today in Basic Science/Genetics...keeping you current
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Knockdown of peroxisome proliferator-activated receptor-beta induces less differentiation and enhances cell–fibronectin adhesion of colon cancer cells
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A novel translational approach for human malignant pleural mesothelioma: heparanase-assisted dual virotherapy
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Primary ex vivo cultures of human fallopian tube epithelium as a model for serous ovarian carcinogenesis
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Paracentesis in Ovarian Cancer: A Study of the Physiology during Free Drainage of Ascites
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How to deal with prognostic factors and radiotherapy results in uterine neoplasms with a sarcomatous component
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Today in Pharmacology/Therapy...keeping you current
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Sorafenib, a dual Raf kinase/vascular endothelial growth factor receptor inhibitor has significant anti-myeloma activity and synergizes with common anti-myeloma drugs
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