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The outcomes of elderly patients with hepatocellular carcinoma treated with transarterial chemoembolization
Cancer, 08/26/09

Yau T et al. – This study has confirmed the comparable efficacy and tolerability in using TACE for the tx of advanced HCC in young and elderly patients

Methods

843 patients ὄ 70 y and 197 patients > 70 y with HCC who received TACE between 1989 and 2006

Results

The overall median survival (14.0 vs. 8.1 mos) and DSS (15.2 vs. 8.7 mos) were significantly higher in elderly than young patients
The most common TACE-related morbidity in both age groups was liver function derangement
Young patients had a significantly higher rate of developing liver derangement after TACE than elderly patients (21% vs. 11%)
Elderly patients had a significantly higher rate of developing PUD with TACE than young patients (2.5% vs. 0.5%)
There was no significant difference in TACE-related mortality between the young and elderly patients (3% vs. 4%)

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