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Sibling versus Unrelated Donor Allogeneic Hematopoietic Cell Transplantation for Chronic Myelogenous Leukemia: Refined HLA Matching Reveals More Graft-versus-Host Disease but not Less Relapse
Biology of Blood and Marrow Transplantation, 08/26/09
Nelson G et al. – The data confirm the applicability of revised HLA–matching scheme in analyzing retrospective data sets when fully informative, allele–level typing is unavailable. In this analysis, greater histoincompatibility can augment GVHD, but does not improve protection against relapse; thus the best donor remains the most closely matched donor.
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