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Human papillomavirus infection in Honduran women with normal cytology
Cancer Causes and Control, 08/24/09
Tábora N et al. - In a trial to estimate type-specific human papillomavirus (HPV) prevalence and its cofactors among Honduran women with normal cytology to provide valuable information to health policymakers about the epidemiology of this important sexually transmitted infection, it was shown that there was a broad diversity of HPV infections, with high-risk types being the most common types detected. Establishment of a well-characterized population with regard to community prevalence of type-specific HPV infection will provide a valuable baseline for monitoring population effectiveness of an HPV vaccine.
Methods- 591 women with normal cytology from Tegucigalpa, Honduras were interviewed and tested for HPV using the SPF10 LiPA25.
- A structured epidemiological questionnaire was administered to each woman.
- Overall HPV prevalence was 51%.
- 23 types of HPV were detected; HPV 16, 51, 31, 18, and 11 were the most common.
- Highest prevalence of cancer associated HPV types (15.0%) was found in the women <35 yrs.
- Besides the association with age, the main independent predictors of HPV infection were the lifetime number of sexual partners and having a low socioeconomic status and <5 previous Pap smears.
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