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Anxiety, depression, and pain: differences by primary cancer
Supportive Care in Cancer, 08/21/09
Fischer DJ et al. - In a study to explore differences in pain, anxiety, and depression by type of primary cancer, it was shown that individuals with cancer undergoing radiation treatment experienced clinically significant levels of unrelieved cancer pain despite standard pain management. Pain intensity and quality ratings were greatest for lung cancer (LC) individuals and may contribute to symptoms of depression. Catastrophizing may contribute to psychological factors that may impact the pain experience. Tailored treatments that meet cancer pts’ psychosocial and medical needs may result in improved pain management and functional ability.
Methods- In a cross-sectional study of consecutive pts (80% male, mean age 60.5 ± 11.5 yrs) undergoing radiation treatment for head/neck (HNC, n = 93), lung (LC, n = 146), or prostate (PC, n = 63) cancers, pts reported pain quality, pattern, and intensity with the McGill Pain Questionnaire.
- They completed the State Trait Anxiety Inventory, Center for Epidemiologic Studies Depression Scale, and Coping Strategies Questionnaire.
- Comparative statistics, correlation coefficients, and multivariate regression analysis were performed.
- Worst pain intensity was significantly greater in LC subjects compared with HNC and PC.
- Pain quality ratings were significantly greater for individuals with LC vs PC, and the regression analyses indicated that pain quality ratings were partially predicted by having LC.
- Depression levels approached clinical significance and were greatest for individuals with LC.
- Catastrophizing was correlated with high levels of depression and anxiety.
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