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Impact of Epidermal Growth Factor Receptor and KRAS Mutations on Clinical Outcomes in Previously Untreated Non–Small Cell Lung Cancer Patients: Results of an Online Tumor Registry of Clinical Trials
Clinical Cancer Research, 08/20/09
Jackman DM et al. – EGFR mutation status is associated with sensitivity to treatment with an EGFR–TKI in patients with advanced non–small cell lung cancer. Patients harboring sensitizing EGFR mutations should be considered for first–line erlotinib or gefitinib.
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