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Sulforaphane induces G2–M arrest and apoptosis in high metastasis cell line of salivary gland adenoid cystic carcinoma
Oral Oncology , 08/19/09
Chu WF et al. – The results suggest SFN inhibits cell growth via inducing G2/M cell arrest and apoptosis in ACC–M cells. These events have been associated with SFN–regulated multiple targets involved in ACC–M cell proliferation. The present study provides an evidence for testing SFN efficacy in vivo and warranting future investigations to exam the clinical potential of SFN in ACC chemotherapy.
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