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Cathepsin G–Mediated Activation of Pro–Matrix Metalloproteinase 9 at the Tumor-Bone Interface Promotes Transforming Growth Factor-beta Signaling and Bone Destruction
Molecular Cancer Research, 08/14/09
Wilson TJ et al. – The authors have identified cathepsin G and MMP9 as proteases involved in enhanced TGF–beta signaling at the tumor–bone interface of mammary tumor–induced osteolytic lesions and have identified these proteases as potential therapeutic targets.
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Today in Basic Science/Genetics...keeping you current
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Prognostic significance of Dicer expression in ovarian cancer - link to global microRNA changes and oestrogen receptor expression
The Journal of Pathology, 12/09/09
Inverse correlation between PDGFC expression and lymphocyte infiltration in human papillary thyroid carcinoma
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Today in Bone/Cartilage...keeping you current
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Enhancement effect of adenovirus-mediated antisense c-myc and caffeine on the cytotoxicity of cisplatin in osteosarcoma cell lines
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