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Antagonism of chemokine receptor CXCR3 inhibits osteosarcoma metastasis to lungs
International Journal of Cancer, 08/17/09
Pradelli E et al. – The results support the hypothesis that CXCR3 and their ligands intervene in the initial dissemination of the osteosarcoma cells to the lungs and stimulate the growth and expansion of the metastatic foci in later stages. Moreover, these studies indicate that targeting CXCR3 may specifically inhibit tumor metastasis without adversely affecting antitumoral host response.
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Today in Basic Science/Genetics...keeping you current
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Knockdown of peroxisome proliferator-activated receptor-beta induces less differentiation and enhances cell–fibronectin adhesion of colon cancer cells
Oncogene, 11/25/09
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Today in Bone/Cartilage...keeping you current
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The value of local treatment in patients with primary, disseminated, multifocal Ewing sarcoma (PDMES)
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Today in Lung/Thoracic Oncology...keeping you current
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A novel translational approach for human malignant pleural mesothelioma: heparanase-assisted dual virotherapy
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