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See Latest ArticlesLactate promotes glioma migration by TGF-{beta}2-dependent regulation of matrix metalloproteinase-2
Neuro-Oncology, 08/11/09
Baumann F et al. – The authors define an LDH–A–induced and TGF–beta2–coordinated regulatory cascade of transcriptional regulation of MMP–2 and integrin v beta 3. This novel interaction between lactate metabolism and TGF–beta2 might constitute a crucial mechanism for glioma migration.
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Today in Basic Science/Genetics...keeping you current
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Expression of p16 in benign and malignant cystic squamous lesions of the neck
Human Pathology, 12/19/09
Correlation of overexpression of HMGA1 and HMGA2 with poor tumor differentiation, invasion, and proliferation associated with let-7 down-regulation in retinoblastomas
Human Pathology, 12/19/09
Beclin 1 and LC3 autophagic gene expression in cutaneous melanocytic lesions
Human Pathology, 12/19/09
Today in Neurologic Oncology...keeping you current
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Phase II trial of erlotinib with temozolomide and radiation in patients with newly diagnosed glioblastoma multiforme
Journal of Neuro-Oncology, 12/17/09
Secretory meningiomas: A benign subgroup causing life-threatening complications
Neuro-Oncology, 12/17/09
Characterization of novel and complex genomic aberrations in glioblastoma using a 32K BAC array
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