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Harnessing the fruits of nature for the development of multi-targeted cancer therapeutics
Cancer Treatment Reviews, 08/07/09
Sarkar FH et al. – In this review article, the authors have succinctly summarized the known effects of “natural products” especially by focusing on isoflavones, indole–3–carbinol (I3C) and its in vivo dimeric product 3,3'–diindolylmethane (DIM), and curcumin, and provided a comprehensive view on the molecular mechanisms underlying the principle of cancer therapy using combination of “natural products” with conventional therapeutics.
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Aloe-emodin induces apoptosis of human nasopharyngeal carcinoma cells via caspase-8-mediated activation of the mitochondrial death pathway
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