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Identification of Gene Signatures and Molecular Markers for Human Lung Cancer Prognosis using an In vitro Lung Carcinogenesis System
Cancer Prevention Research, 08/12/09
Kadara H et al. – Stage I NSCLC patients with positive UBE2C expression exhibited significantly poorer overall and progression–free survival than patients with negative expression. The studies with this in vitro model have lead to the identification of a robust six–gene signature, which may be valuable for predicting the survival of lung adenocarcinoma patients. Moreover, one of those genes, UBE2C, seems to be a powerful biomarker for NSCLC survival prediction.
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Today in Lung/Thoracic Oncology...keeping you current
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