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Benson AB et al. – The review demonstrates that critically ill patients are more susceptible to TRALI and require special attention by critical care specialists, haematologists and transfusion medicine experts. Further research is required into TRALI and its pathogenesis so that transfusions are safer and administered appropriately. Avoidance including male–only transfusion practises, the use of leucoreduced components, fresher blood/blood components and solvent detergent plasma are also discussed.



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