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Dietary patterns and risk of oral cancer: A factor analysis study of a population in Jakarta, Indonesia
Oral Oncology , 08/06/09
Amtha R et al. - In a study to determine the association between dietary pattern and oral cancer in a Jakarta population using factor analysis, it was concluded that factor analysis may be useful to determine the diet pattern of a big set of food type and establish the correlation with oral cancer.
Methods- Dietary data were collected using a food frequency questionnaire and factor analysis was performed on 15 food groups resulting in 4 principle factors/components being retained.
- The first factor “preferred” was characterized by fast food, fermented food, canned food, snacks high in fat and sugar, cooked and raw vegetables, and seafood.
- The second factor labeled “combination” was loaded by the intake of dairy product, red meat, white meat and fruits.
- The third factor labeled “chemical related" was loaded by processed food and monosodium glutamate and the fourth principle component consisted of drinks and grain was labeled as “traditional.”
- Conditional logistic regression was done using STATA 8 to obtain the odds ratio (OR) of highest tertile of each component retained from factor analysis and ORs were then adjusted with risk habits.
- Consumption of the highest tertile of the “preferred” pattern increased the risk of oral cancer by 2-times vs the lowest tertile of consumption.
- "Chemical related” pattern showed higher risk of about 3-fold, while the “traditional” pattern showed an increased of risk by 2-fold.
- The “combination” pattern displayed protective effects in relation to oral cancer.
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