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Targeted Activation of Innate Immunity for Therapeutic Induction of Autophagy and Apoptosis in Melanoma Cells
Cancer Cell, 08/07/09
Tormo D et al. – A concurrent activity of the dsRNA helicase MDA–5 driving the proapoptotic protein NOXA resulted in an efficient autodigestion of melanoma cells. These results reveal tractable links for therapeutic intervention among dsRNA helicases, endo/lysosomes, and apoptotic factors.
Today in Carcinogenesis...keeping you current
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Antitumorigenic effects of cannabinoids beyond apoptosis
Journal of Pharmacology and Experimental Therapeutics, 11/06/09
The emerging role of the distal Fallopian tube and p53 in pelvic serous carcinogenesis
The Journal of Pathology, 11/05/09
Warburg effect revisited: an epigenetic link between glycolysis and gastric carcinogenesis
Oncogene, 11/05/09
Today in Dermatologic Oncology...keeping you current
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A Multimarker Prognostic Assay for Primary Cutaneous Melanoma
Clinical Cancer Research, 11/06/09
Detection of BRAF mutations in the tumour and serum of patients enrolled in the AZD6244 (ARRY-142886) advanced melanoma phase II study
British Journal of Cancer, 11/03/09
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