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Amongst eligible patients, age and comorbidity do not predict for dose-limiting toxicity from phase I chemotherapy
Cancer Chemotherapy and Pharmacology, 08/05/09
LoConte NK et al. – Age and comorbidity did not predict for development of DLT in phase I chemotherapy trials. Many of these pts were very fit, with relatively low CIRS–G scores, so the impact of comorbidity may not have been fully evaluated. Several social and clinical factors may predict for development of DLT. A prospective study is being planned to confirm these results.
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Immunoglobulin G Fc Receptor FcgammaRIIIa 158 V/F Polymorphism Correlates With Rituximab-Induced Neutropenia After Autologous Transplantation in Patients With Non-Hodgkin's Lymphoma
Journal of Clinical Oncology, 12/04/09
Cytidine Deaminase Residual Activity in Serum Is a Predictive Marker of Early Severe Toxicities in Adults After Gemcitabine-Based Chemotherapies
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