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A correlation between growth rate, apoptosis, and tumor necrosis factor-alpha in umbilical cord blood cells infected with two strains of Mycobacterium tuberculosis
Transfusion, 08/11/09
Theus JW et al. – The TNF–alpha response of the UCB cells is related to the infecting strain and the intracellular growth of the strain of Mycobacterium tuberculosis is not directly controlled by the level of TNF–alpha. This cytokine is at the start of a powerful cascade of transcription factors with numerous pleiotropic effects; consequently abrogating/enhancing a single direct outcome was difficult, with only slight alterations in growth.
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Today in Basic Science/Genetics...keeping you current
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The tumour necrosis factor as a mediator of vessel inflammation: importance of exposed receptor residues for its neutralization
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Frequency and prognostic significance of murine double minute protein-2 overexpression and p53 gene mutations in childhood acute lymphoblastic leukemia
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Today in Transfusion Medicine...keeping you current
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Safety and sensitivity of two ultrasound strategies in patients with clinically suspected deep venous thrombosis: a prospective management study
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