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Kinome Profiling of Chondrosarcoma Reveals Src-Pathway Activity and Dasatinib as Option for Treatment
Cancer Research, 08/04/09
Schrage YM et al. – Using kinome profiling, the authors found the Src pathway to be active in chondrosarcoma. Moreover, the authors showed in vitro that the inhibitor of the Src pathway, dasatinib, may provide a potential therapeutic benefit for chondrosarcoma patients who are not eligible for surgery.
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Today in Bone/Cartilage...keeping you current
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Smad2 and Smad3 have opposing roles in breast cancer bone metastasis by differentially affecting tumor angiogenesis
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