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Anticancer and cancer chemopreventive potential of grape seed extract and other grape-based products
The Journal of Nutrition, 08/11/09
Kaur M et al. – In a review of the anticancer and cancer chemopreventive potential of grape seed extract and other grape-based products, this review focuses on recent advancements in cancer chemopreventive and anticancer efficacy of grape seed extract and other grape-based products. Completed studies from various scientific groups conclude that both grapes and grape-based products are excellent sources of various anticancer agents and their regular consumption should be beneficial to the general population.
Methods- Intervention or prevention of cancer by dietary constituents, a strategy defined as chemoprevention, holds great promise in the quest to control cancer, because it can be implemented on a broader population base with less economic burden.
- Several epidemiological studies have shown that populations that consume diets rich in fruits and vegetables have an overall lower cancer incidence.
- Research efforts have focused on identifying, characterizing, and providing scientific basis to the efficacy of various phytonutrients in an effort to develop effective strategy to control various human malignancies.
- Cancer induction, growth, and progression are multi-step events and numerous studies have demonstrated that various dietary agents interfere with these stages of cancer, thus blocking malignancy.
- Fruits and vegetables represent untapped reservoir of various nutritive and nonnutritive phytochemicals with potential cancer chemopreventive activity.
- Grapes and grape-based products are 1 such class of dietary products that have shown cancer chemopreventive potential and are also known to improve overall human health.
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