Your Messages Inbox
Most Viewed Abstracts
1. Report Shows Shift in Starting Salaries for Physicians 2. Recommendations on the use of 18F-FDG PET in oncology 3. Taxane-based combinations as adjuvant chemotherapy of early breast cancer: a meta-analysis of randomized trials 4. Gene expression signatures, clinicopathological features, and individualized therapy in breast cancer 5. Sentinel node biopsy is important in mastectomy for ductal carcinoma in situ
Top Ten Searches
brca1 prostate-specific antigen sclc fobt egd bmi dysplasia hematologic ovarian hccYour Article Summary
See Latest ArticlesComparative proteomical and metalloproteomical analyses of human plasma from patients with laryngeal cancer
Cancer Immunology, Immunotherapy, 08/04/09
Gomes CPC et al. – In a study to evaluate the plasmas of pts with laryngeal cancer, the study reinforces the importance of the immune response as target in the understanding and treatment of laryngeal cancer and the possibility that chromium is important in the carcinogenic progress.
Methods- Plasmas of pts with laryngeal cancer and of healthy smokers were evaluated by 2D gel electrophoresis and mass spectrometry.
- Proteins were detected on every gel around pH 4.0–10.0 from molecular mass of 10–60 kDa.
- Few differences were found among cancer and control pts.
- 3 spots gathered between pI 7.3 and 7.6 with different molecular masses appeared exclusively in cancer profiles.
- From 10 spots identified, 6 correspond to immune system components, including the 3 differential ones.
- The latter were observed only in cancer pts.
- Presence of several trace elements in the identified proteins was determined by inductively coupled plasma mass spectrometry, where chromium was increased in all proteins analyzed from pts with cancer.
Octavio Luiz Franco, 07/28/09
| Data reported in this article associate the use of proteomics and metallo-proteomics in order to understand the immune response modifications in human plasma of patients with laryngheal cancer |
Related Articles
Advantages and limitations of the autofluorescent diagnostics of the laryngeal cancer and precancerosis
European Archives of Oto-Rhino-Laryngology, 11/17/09
Relevance Score: 68%
Nuclear factor-[kappa]B expression as a novel marker of radioresistance in early-stage laryngeal cancer
Head & Neck, 11/09/09
Relevance Score: 68%
Staging of Laryngeal Cancer Using 64-Channel Multidetector Row CT: Comparison of Standard Neck CT with Dedicated Breath-Maneuver Laryngeal CT
American Journal of Neuroradiology, 11/10/09
Relevance Score: 67%
Asbestos exposure and laryngeal cancer: Is there an association
ENT Journal, 10/16/09
Relevance Score: 67%
Gender Effects on Airway Closure in Head and Neck Cancer Patients
Dysphagia, 10/26/09
Relevance Score: 66%
Today in Head and Neck...keeping you current
Receive free subspecialty "5-minute updates" via email
Radiation Treatment Interruptions Greater Than One Week and Low Hemoglobin Levels (12 g/dL) are Predictors of Local Regional Failure After Definitive Concurrent Chemotherapy and Intensity-Modulated Radiation Therapy for Squamous Cell Carcinoma of the Head and Neck
American Journal of Clinical Oncology, 12/07/09
Failure to Diagnose and Delayed Diagnosis of Cancer
The Journal of the American Dental Association , 12/07/09
Prospective study of daily low-dose nedaplatin and continuous 5-fluorouracil infusion combined with radiation for the treatment of esophageal squamous cell carcinoma
BMC Cancer, 12/04/09
Sponsor
Article Search
Sponsor
Sponsor