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Dexrazoxane-afforded protection against chronic anthracycline cardiotoxicity in vivo: effective rescue of cardiomyocytes from apoptotic cell death
British Journal of Cancer, 07/24/09
Popelova O et al. – The study identifies inhibition of apoptosis as an important target for effective cardioprotection against chronic anthracycline cardiotoxicity and suggests that lipoperoxidation–independent mechanisms are involved in the cardioprotective action of DEX.
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