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Autoimmune pancreatitis: differentiation from pancreatic carcinoma and normal pancreas on the basis of enhancement characteristics at dual-phase CT
American Journal of Roentgenology, 07/28/09

Takahashi N et al. - In a study to define the pancreatic enhancement of autoimmune pancreatitis at dual-phase CT and to compare it with that of pancreatic carcinoma (PCa) and a normal pancreas, it seems that with dual-phase CT, enhancement patterns of the pancreas and pancreatic masses in pts with autoimmune pancreatitis are different from those of PCa and normal pancreas.

Methods

Dual-phase CT scans of 101 pts (43 with autoimmune pancreatitis, 13 cases of which were focal; 33 with PCa, and 25 with a normal pancreas) were evaluated.
1 radiologist measured CT attenuation of the pancreatic parenchyma and pancreatic masses in both the pancreatic and hepatic phases of imaging.
Mean CT attenuation value of the pancreatic parenchyma in pts with autoimmune pancreatitis was compared with that in pts with a normal pancreas.
Mean CT attenuation value of the focal masses in the focal form of autoimmune pancreatitis was compared with that of carcinomas.

Results

In the pancreatic phase, mean CT attenuation value of the pancreatic parenchyma in pts with autoimmune pancreatitis was significantly lower than that in pts with a normal pancreas (autoimmune pancreatitis, 85 HU; normal pancreas, 104 HU).
In the hepatic phase, mean CT attenuation values were not significantly different (autoimmune pancreatitis, 96 HU; normal pancreas, 89 HU).
In the pancreatic phase, mean CT attenuation value of the mass in autoimmune pancreatitis was not significantly different from that of carcinoma (autoimmune pancreatitis, 71 HU; carcinoma, 59 HU), but in the hepatic phase, the value was significantly higher than that of carcinoma (autoimmune pancreatitis, 90 HU; carcinoma, 64 HU).

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