Oncology Medical News about Intracerebral schwannoma

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Intracerebral schwannoma in a child with infiltration along perivascular spaces resembling meningioangiomatosis
Pathology International, 07/23/09

Ishihara M et al. – A few intratumoral axons, seen on immunostaining for neurofilament protein, were trapped at the periphery of the main lesion, but there was no evidence of intralesional axons in the multiple nodules of Schwann cell proliferations that extended into the perivascular spaces, suggesting that the lesions are neoplastic. Because Schwann cells are not a natural component of the central nervous system, the origin of intracerebral schwannomas remains unknown. The histology suggests that Schwann cells of the perivascular nerve plexus are a likely site of origin.

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