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Molecular basis of the RHD gene in blood donors with DEL phenotypes in Shanghai
Vox Sanguinis, 07/24/09
Li Q et al. – About 4·35% apparent D negative Chinese individuals were weak D or partial D, while 17·60% were DEL. Novel DEL alleles are rare, and all but 11 of the 279 DELs were due to the most common DEL allele, RHD (K409 K). The RHD 3G > A might be the second most frequent DEL allele in Chinese. Exploration of a complete molecular basis for DEL in Chinese ethnic groups is a long–term endeavour.
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