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Human Leukocyte Antigen-G Protein Expression Is an Unfavorable Prognostic Predictor of Hepatocellular Carcinoma following Curative Resection
Clinical Cancer Research, 07/22/09
Cai MY et al. – Overexpression of HLA–G protein in HCC was an independent indicator for poor outcome especially in early–stage disease. The combination of HLA–G expression and Tregs/CD8+ ratio added the prognostic power to both variables, offering a possible strategy of tumor–stroma interaction–oriented cancer immunotherapy.
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