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MiR-122/Cyclin G1 Interaction Modulates p53 Activity and Affects Doxorubicin Sensitivity of Human Hepatocarcinoma Cells
Cancer Research, 07/20/09
Fornari F et al. – In patients resected for HCC, lower miR–122 levels were associated with a shorter TTR, whereas higher cyclin G1 expression was related to a lower survival, suggesting that miR–122 might represent an effective molecular target for HCC. The findings establish a basis toward the development of combined chemo– and miRNA–based therapy for HCC treatment.
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Today in Basic Science/Genetics...keeping you current
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Expression of p16 in benign and malignant cystic squamous lesions of the neck
Human Pathology, 12/19/09
Correlation of overexpression of HMGA1 and HMGA2 with poor tumor differentiation, invasion, and proliferation associated with let-7 down-regulation in retinoblastomas
Human Pathology, 12/19/09
Beclin 1 and LC3 autophagic gene expression in cutaneous melanocytic lesions
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Today in Hepatobiliary/Pancreas...keeping you current
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Isolated recurrence of distal adenocarcinoma of the extrahepatic bile duct on a draining sinus scar after curative resection: Case Report and review of the literature
World Journal of Surgical Oncology, 12/16/09
An insertion/deletion polymorphism at miRNA-122-binding site in the interleukin-1alpha 3' untranslated region confers risk for hepatocellular carcinoma
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Liver transplantation for primary hepatic leiomyosarcoma: a case report and review of the literatures
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