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Duplication of 7q34 is specific to juvenile pilocytic astrocytomas and a hallmark of cerebellar and optic pathway tumours
British Journal of Cancer, 07/20/09
Jacob K et al. – The results suggest that variants of JPA might arise from a unique site–restricted progenitor cell where 7q34 duplication, a hallmark of this tumour–type in association to MAPK–kinase pathway activation, potentially plays a site–specific role in their pathogenesis.
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Today in Basic Science/Genetics...keeping you current
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Multi-step binding of ADAMTS-13 to von Willebrand factor
Journal of Thrombosis and Haemostasis, 12/02/09
Combined genetic effect of CDK7 and ESR1 polymorphisms on breast cancer
Breast Cancer Research and Treatment, 12/02/09
UHRF1 is associated with epigenetic silencing of BRCA1 in sporadic breast cancer
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Today in Pediatric Heme/Oncology...keeping you current
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Current Approach to Pediatric Soft Tissue Sarcomas
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Frequency and prognostic significance of murine double minute protein-2 overexpression and p53 gene mutations in childhood acute lymphoblastic leukemia
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Germline Genetic Variation in an Organic Anion Transporter Polypeptide Associated With Methotrexate Pharmacokinetics and Clinical Effects
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