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Jacob K et al. – The results suggest that variants of JPA might arise from a unique site–restricted progenitor cell where 7q34 duplication, a hallmark of this tumour–type in association to MAPK–kinase pathway activation, potentially plays a site–specific role in their pathogenesis.

Today in Basic Science/Genetics...keeping you current

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UHRF1 is associated with epigenetic silencing of BRCA1 in sporadic breast cancer
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