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Azacitidine for the treatment of myelodysplastic syndrome
Expert Review of Anticancer Therapy, 07/13/09
Cataldo VD et al. - The pyrimidine nucleoside analog azacitidine, which inhibits DNA methyltransferases, has recently become the first therapeutic to prolong survival in patients with MDS, thus changing the natural history of these malignancies. The activity of azacitidine in MDS has spurred the development of combinations of this agent with other epigenetic modifiers for the treatment of MDS and AML.
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The role of azacitidine in the management of myelodysplastic syndromes (MDS)
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Relevance Score: 87%
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Safety and Efficacy of Romiplostim in Patients With Lower-Risk Myelodysplastic Syndrome and Thrombocytopenia
Journal of Clinical Oncology, 12/20/09
Targeting the Fanconi Anemia/BRCA Pathway Circumvents Drug Resistance in Multiple Myeloma
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Telomere shortening and chromosomal instability in myelodysplastic syndromes
Genes, Chromosomes and Cancer, 12/20/09
Today in Pharmacology/Therapy...keeping you current
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Safety and Efficacy of Romiplostim in Patients With Lower-Risk Myelodysplastic Syndrome and Thrombocytopenia
Journal of Clinical Oncology, 12/20/09
Phase II Trial of Infusional Fluorouracil, Irinotecan, and Bevacizumab for Metastatic Colorectal Cancer: Efficacy and Circulating Angiogenic Biomarkers Associated With Therapeutic Resistance
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