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See Latest ArticlesChemo-sensitivity in a panel of B-cell precursor acute lymphoblastic leukemia cell lines, YCUB series, derived from children
Leukemia Research, 07/13/09
Goto H et al. - Of the drugs tested, etoposide and SN-38 (irinotecan) showed highest efficacy in the panel, with 50% growth inhibition at 0.22–1.8 ug/ml and 0.57–3.6 ng/ml, respectively. This cell line panel offers an in vitro model for the development of new therapies for childhood BCP-ALL.
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Today in Basic Science/Genetics...keeping you current
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HER2 overexpression and amplification is present in a subset of ovarian mucinous carcinomas and can be targeted with trastuzumab therapy
BMC Cancer, 12/20/09
Telomere shortening and chromosomal instability in myelodysplastic syndromes
Genes, Chromosomes and Cancer, 12/20/09
The mitogen-activated protein kinase signaling pathways: role in megakaryocyte differentiation
Journal of Thrombosis and Haemostasis, 12/20/09
Today in Leukemia/Lymphoma...keeping you current
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Nilotinib As Front-Line Treatment for Patients With Chronic Myeloid Leukemia in Early Chronic Phase
Journal of Clinical Oncology, 12/20/09
Cytogenetics of long-term survivors of ETV6-RUNX1 fusion positive acute lymphoblastic leukemia
Genes, Chromosomes and Cancer, 12/19/09
microRNAs in acute myeloid leukemia: Expression patterns, correlations with genetic and clinical parameters, and prognostic significance
Genes, Chromosomes and Cancer, 12/19/09
Today in Pediatric Heme/Oncology...keeping you current
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Pharmacogenetic risk factors for altered bone mineral density and body composition in pediatric acute lymphoblastic leukemia
Haematologica, 12/19/09
Distinct features of colorectal cancer in children and adolescents
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Feasibility and efficacy of chronic transfusion for stroke prevention in children with sickle cell disease
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