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Helicobacter pylori virulence factors in gastric carcinogenesis
Cancer Letters, 07/10/09
Wen S et al. - The strongest candidates are genes within the cag (cytotoxin-associated antigen) pathogenicity island, including the gene encoding the CagA protein, as well as polymorphic variation in the VacA vacuolating exotoxin and the blood group antigen binding adhesin BabA. Improved understanding of the pathogenesis of H. pylori-associated gastric cancer may improve risk stratification for prevention and therapy.
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Today in Carcinogenesis...keeping you current
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Regulating the leukaemia stem cell
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