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See Latest ArticlesEpidermal Notch1 Loss Promotes Skin Tumorigenesis by Impacting the Stromal Microenvironment
Cancer Cell, 07/09/09
Demehri S et al. - Loss of other Notch paralogues that impaired the skin barrier also predisposed Notch1-expressing skin to tumorigenesis, demonstrating that the tumor-promoting effect of Notch1 loss involves a crosstalk between barrier-defective epidermis and its stroma.
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