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Parathyroid Hormone-Related Protein Regulates Cell Survival Pathways via Integrin alpha6 beta4-Mediated Activation of Phosphatidylinositol 3-Kinase/Akt Signaling
Molecular Cancer Research, 07/14/09
Bhatia V et al. - The observations provide evidence of a link between PTHrP and the PI3K/Akt signaling pathway through integrin alpha6 beta4, resulting in the activation of survival pathways. Targeting PTHrP production in prostate cancer may thus prove therapeutically beneficial.
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Today in Basic Science/Genetics...keeping you current
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Integrated Molecular and Clinical Analysis of AKT Activation in Metastatic Melanoma
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Today in Endocrine Oncology...keeping you current
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Poorly Differentiated Thyroid Carcinoma: 5 Years after the 2004 WHO Classification of Endocrine Tumours
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Blood dosimetry from a single measurement of the whole body radioiodine retention in patients with differentiated thyroid carcinoma
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