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A novel l218p mutation in nadh-cytochrome b5 reductase associated with type i recessive congenital methemoglobinemia
Pediatric Hematology and Oncology, 07/08/09

Arnkoglu T et al. - Sequencing the CYB5R3 gene identified a homozygous T-C transition at base c.653, which changed codon 218 from leucine to proline (L218P) in cb5r protein. Treatment with ascorbic acid relieved the cyanosis and returned methemoglobin levels to normal.


Today in Anemia/Polycythemia...keeping you current

Update on the use of deferasirox in the management of iron overload
Therapeutics and Clinical Risk Management, 11/05/09

Effect of combination therapy of hydroxyurea with l-carnitine and magnesium chloride on hematologic parameters and cardiac function of patients with beta-thalassemia intermedia
European Journal of Haematology, 11/04/09

Effect of Epoetin Alfa on Survival and Cancer Treatment-Related Anemia and Fatigue in Patients Receiving Radical Radiotherapy With Curative Intent for Head and Neck Cancer
Journal of Clinical Oncology, 11/09/09

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Today in Pediatric Heme/Oncology...keeping you current

Comparison of neurocognitive functioning in children previously randomly assigned to intrathecal methotrexate compared with triple intrathecal therapy for the treatment of childhood acute lymphoblastic leukemia
Journal of Clinical Oncology, 11/09/09

The impact of prophylactic fresh frozen plasma and cryoprecipitate on the incidence of CNS thrombosis and hemorrhage in children with acute lymphoblastic leukemia receiving asparaginase
Blood, 11/02/09

Medulloblastoma in childhood: revisiting intrathecal therapy in infants and children
Cancer Chemotherapy and Pharmacology, 10/29/09

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