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See Latest ArticlesSequestration of E12/E47 and suppression of p27KIP1 play a role in Id2-induced proliferation and tumorigenesis
Carcinogenesis, 07/02/09
Rosenthal DS et al. - Id2 is a member of the helix-loop-helix (HLH) family of transcription regulators known to antagonize basic HLH transcription factors and proteins of the retinoblastoma tumor suppressor family and is implicated in the regulation of proliferation, differentiation, apoptosis and carcinogenesis. The results tie together the previously observed misregulation of Id2 with a novel mechanism for tumorigenesis.
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Today in Basic Science/Genetics...keeping you current
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Gene expression profiling identifies emerging oncogenic pathways operating in extranodal NK/T-cell lymphoma, nasal-type
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The sumoylation pathway is dysregulated in multiple myeloma and is associated with adverse patient outcome
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TCEAL7, a putative tumor suppressor gene, negatively regulates NF-kappaB pathway
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Today in Carcinogenesis...keeping you current
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Regulating the leukaemia stem cell
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