Most Viewed Abstracts
1. Report Shows Shift in Starting Salaries for Physicians 2. Recommendations on the use of 18F-FDG PET in oncology 3. Taxane-based combinations as adjuvant chemotherapy of early breast cancer: a meta-analysis of randomized trials 4. Gene expression signatures, clinicopathological features, and individualized therapy in breast cancer 5. Sentinel node biopsy is important in mastectomy for ductal carcinoma in situ
Top Ten Searches
brca1 prostate-specific antigen sclc fobt egd bmi dysplasia hematologic ovarian hccYour Article Summary
Determinants of recovery from amenorrhea in premenopausal breast cancer patients receiving adjuvant chemotherapy in the taxane era
Anti-Cancer Drugs, 07/02/09
Minisini AM et al. - In a trial to retrospectively analyze the incidence of amenorrhea after adjuvant chemotherapy and subsequent recovery of menses in 145 breast cancer pts, it was determined that recovery of menses after chemotherapy-induced amenorrhea occurs more probably in younger women, with no pregnancies and receiving taxanes.
Methods- Incidence of amenorrhea after adjuvant chemotherapy and subsequent recovery of menses were analyzed in 145 breast cancer pts.
- Age, smoking, alcohol consumption, body mass index, chemotherapy regimen, previous hormonal therapies, and previous childbearing were analyzed as potential predictive factors of ovarian function recovery.
- Median age was 42 yrs at the beginning of adjuvant chemotherapy with 30.3% of pts below 40 yrs of age.
- The majority (87.6%) of pts received anthracycline-based chemotherapy, 35.2% of pts received a cyclophosphamide-methotrexate-5-fluorouracil regimen, and 42.8% received a taxane.
- Incidence of chemotherapy-induced amenorrhea was 80, and 35.3% of these pts resumed menses after a median of 8 mos.
- Younger age (<40 yrs) and taxane-based chemotherapy were associated with increased probability of recovery of menses after chemotherapy-induced amenorrhea.
- Cyclophosphamide-methotrexate-5-fluorouracil-based chemotherapy and previous childbearing were associated with an increased probability of permanent chemotherapy-induced amenorrhea.
Related Articles
Assessment of Myocardial Ischemic Memory Using Persistence of Post-Systolic Thickening After Recovery From Ischemia
JACC - Journal of the American College of Cardiology: Cardiovascular Imaging, 11/16/09
Relevance Score: 66%
Muscle and bone follow similar temporal patterns of recovery from muscle-induced disuse due to botulinum toxin injection
Bone, 11/12/09
Relevance Score: 66%
Delayed cerebral thrombosis after initial good recovery from pneumococcal meningitis
Neurology, 11/06/09
Relevance Score: 66%
Effects of maintaining a remifentanil infusion on the recovery profiles during emergence from anaesthesia and tracheal extubation
British Journal of Anesthesia, 11/02/09
Relevance Score: 66%
Evaluation of automated and manual commercial DNA extraction methods for the recovery of Brucella spp. DNA from suspensions and spiked swabs
Journal of Clinical Microbiology, 10/23/09
Relevance Score: 66%
Today in Breast...keeping you current
Receive free subspecialty "5-minute updates" via email
Gene set enrichment analysis provides insight into novel signalling pathways in breast cancer stem cells
British Journal of Cancer, 12/10/09
Subtypes of familial breast tumours revealed by expression and copy number profiling
Breast Cancer Research and Treatment, 12/10/09
Evaluation of screening instruments for depression and anxiety in breast cancer survivors
Breast Cancer Research and Treatment, 12/10/09
Today in Gynecologic Oncology...keeping you current
Receive free subspecialty "5-minute updates" via email
Semiquantitative assessment of the microdistribution of fluorescence-labeled monoclonal antibody in small peritoneal disseminations of ovarian cancer
Cancer Science, 12/10/09
MiR-15a and MiR-16 Control Bmi-1 Expression in Ovarian Cancer
Cancer Research, 12/10/09
Epigenetic Repression of microRNA-129-2 Leads to Overexpression of SOX4 Oncogene in Endometrial Cancer
Cancer Research, 12/10/09
Today in Pharmacology/Therapy...keeping you current
Receive free subspecialty "5-minute updates" via email
18FDG-PET-CT in the follow-up of non-small cell lung cancer patients after radical radiotherapy with or without chemotherapy: An economic evaluation
European Journal of Cancer, 12/10/09
MicroRNAs: Predictors and modifiers of chemo- and radiotherapy in different tumour types
European Journal of Cancer, 12/10/09
Phase I trial of 17-dimethylaminoethylamino-17-demethoxygeldanamycin (17-DMAG), a heat shock protein inhibitor, administered twice weekly in patients with advanced malignancies
European Journal of Cancer, 12/10/09
Sponsor
Article Search
Sponsor
Sponsor


See Latest Articles


