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See Latest ArticlesNew cytotoxic rosamine derivatives selectively accumulate in the mitochondria of cancer cells
Anti-Cancer Drugs, 07/02/09
Lim SH et al. - In subsequent experiments, the para-iodo aryl substituted rosamine was found to localize exclusively within the mitochondria and induced apoptosis as the major mode of cell death. The results suggest that these compounds offer potential for the design of mitochondria-targeting agents that either directly kill or deliver cytotoxic drugs to selectively kill cancer cells.
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Today in Basic Science/Genetics...keeping you current
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Knockdown of peroxisome proliferator-activated receptor-beta induces less differentiation and enhances cell–fibronectin adhesion of colon cancer cells
Oncogene, 11/25/09
A novel translational approach for human malignant pleural mesothelioma: heparanase-assisted dual virotherapy
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Embryoid body formation of human amniotic fluid stem cells depends on mTOR
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