Oncology Medical News about Pediatric Brain Tumors

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Pediatric brain tumors: current treatment strategies and future therapeutic approaches
Neurotherapeutics, 07/06/09

Mueller S et al. - In a review of current treatment strategies and future therapeutic approaches for pediatric brain tumors, this article will outline current and future therapeutic strategies for the most common pediatric CNS tumors, including primitive neuroectodermal tumors such as medulloblastoma, as well as astrocytomas and ependymomas.

Methods

Pediatric CNS tumors are the most common solid tumors of childhood and the second most common cancer after hematological malignancies accounting for approximate 20 to 25% of all primary pediatric tumors.
With over 3000 new cases per yr in the US, childhood CNS tumors are the leading cause of death related to cancer in this population.

Results

Prognosis for these pts has improved over the last few decades, but current therapies continue to carry a high risk of significant side effects, especially for the very young.
A combination of surgery, radiation, and chemotherapy is often used in children >3 yrs of age.

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