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See Latest ArticlesSOCS1 protects protein tyrosine phosphatases by thioredoxin upregulation and attenuates Jaks to suppress ROS-mediated apoptosis
Oncogene, 07/01/09
Oh J et al. - The data strongly suggest that both the protection of PTPs by thioredoxin from ROS attack and the attenuation of Jaks account for the antiapoptotic function of SOCS1 in immune cells under oxidative stress.
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Integrated Molecular and Clinical Analysis of AKT Activation in Metastatic Melanoma
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