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Van Cutsem E et al. - In a trial to investigate whether the addition of irinotecan to the de Gramont infusional fluorouracil (FU)/leucovorin (LV) adjuvant regimen (LV5FU2) would improve disease-free survival (DFS) in pts with stage III colon cancer, it was reported that irinotecan added to LV5FU2 as adjuvant therapy did not confer a statistically significant improvement in DFS or overall survival (OS) in pts with stage III colon cancer vs LV5FU2 alone.

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