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See Latest ArticlesNelfinavir induces mitochondria protection by ERK1/2-mediated mcl-1 stabilization that can be overcome by sorafenib
Investigational New Drugs, 07/01/09
Bruning A et al. - The combination of nelfinavir with sorafenib induced mitochondrial membrane potential disruption and resulted in an improved activity of nelfinavir on ovarian cancer cells. Thus, a combination of these two investigational anti-cancer drugs could be of interest especially because of their unique mechanism of apoptosis induction even in otherwise chemo-resistant human cancer cells.
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Today in Gynecologic Oncology...keeping you current
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Recreational physical activity and risk of epithelial ovarian cancer
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Gonadotropin and steroid receptors as prognostic factors in advanced ovarian cancer: a retrospective study
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Today in Pharmacology/Therapy...keeping you current
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Intensive chemotherapy improves survival in pediatric high-grade glioma after gross total resection: results of the HIT-GBM-C protocol
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The combination of thalidomide, cyclophosphamide and dexamethasone is potentially useful in highly resistant Hodgkins lymphoma
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